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Ibutamoren (MK-677)

(103 customer reviews)

$32.41 – $181.17

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Description

 

Ibutamoren (MK-677) – Product Information

Ibutamoren, which is often referred to as MK-677, is a growth hormone secretagogue that functions similarly to ghrelin. The main reason for its research is that it may raise the body’s level of growth hormone (GH) and insulin like growth factor (IGF-1).

Ibutamoren is not approved for human consumption and is used strictly for research purposes only.

Mechanism of Action

Ibutamoren binds to and activates the ghrelin receptors (GHS-R1a) in the brain, particularly in the hypothalamus and pituitary gland. While MK-677 primarily affects the GH axis, it may indirectly influence the HPG axis.

Activation of these receptors stimulates the pituitary gland to increase the secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). By mimicking ghrelin, MK-677 boosts the natural production of GH without directly stimulating androgen receptors or affecting the hypothalamic-pituitary-gonadal (HPG) axis. The increase in GH and IGF-1 levels promotes muscle growth, fat loss, and improved bone density, similar to the effects of exogenous GH administration. Unlike anabolic steroids or selective androgen receptor modulators (SARMs), MK-677 does not interact with androgen receptors, making it distinct in its action and classification.

Potential Benefits

  • Potentially Increased Muscle Mass: Ibutamoren might help stimulate growth hormone production, leading to an increase in lean muscle mass. This makes it a potential candidate for combating muscle wasting conditions.
  • Potentially Enhanced Bone Density: MK-677 may aid in boosting bone mineral density by encouraging the production of growth hormone.More research is needed to confirm any significant effects on bone mineral density.
  • Improved Recovery and Healing: Ibutamoren’s ability to elevate IGF-1 levels supports faster recovery and healing of issues, making it a focus of studies related to injury rehabilitation.
  • Better Sleep Quality: MK-677 may have a potential impact on sleep quality, but more research is needed.
  • Reduction in Body Fat: may aid in reducing body fat by boosting basal metabolic rate, although more research is needed to confirm this effect.

Side Effects

  • Increased Appetite: Ibutamoren increases appetite by stimulating the ghrelin receptor, which signals hunger, leading to a potential increase in food intake.
  • Lower- Extremity Edema: Although fluid retention is usually moderate and goes away with time, it has been found in few cases, especially in the lower extremities.

MK-677 and Growth Hormone

A study was conducted to determine the effect of MK-677 on growth hormone release in obese subjects. The study involved oral treatment of MK-677 and recruited twenty-four healthy obese subjects. The impact of oral administration of MK 677 on GH secretion was observed.

The final results showed that there was a significant increase in GH levels. Another encouraging sign was that the increase persisted at 2 and 8 weeks of treatment. It was also observed that the initial dose of MK-677 produced a greater increase in GH levels than any of the upcoming doses.

MK-677 and IGF-1

Insulin-like growth factor 1 is a hormone that plays many crucial functions in the human body. These include fetal development, childhood growth, and anabolic effects in adults. Aside from that, IGF-1 has also been proven to help with muscle regeneration and offer neural protective effects.

MK-677 and Bone Density

There is a direct relationship between GH levels in the body and bone mineral density. Various studies show that an increase in GH leads to stronger bones. That explains why older adults, who have lower GH levels than their younger counterparts, tend to have weaker bones.

Research involving elderly adults found that MK-677 has the potential to stimulate bone turnover and increase bone deposition and formation. However, more research is needed.

MK-677 and Sleep Quality

Sleep is one of the most essential body functions. Research has shown that a good night’s sleep can boost learning, decision-making, memory, and creativity. What’s more, short sleep duration and poor sleep quality are linked to mass muscle reduction.

To determine the impact of MK-677 on sleep quality, one study group was administered this GH secretagogue while the other was given a placebo. Results showed that the MK-677 group had a 20% increase in REM sleep and a 50% increase in the duration of stage IV compared to the placebo group.

Clinical Research

Some studies exist, the volume of human clinical trials is limited, and more are needed. It was demonstrated that Ibutamoren significantly raised GH and IGF-1 levels in both healthy and obese patients in double-blind, randomized, controlled experiment. Its ability to restore muscular strength and reverse muscle wasting in older patients with hip fractures was also noted in another study.

Furthermore, studies indicate that ibutamoren may increase bone production and turnover, which may have a beneficial effect on bone density, especially in older persons.

FAQs

Where to Buy MK677 for Research Purposes?

PureRawz offers free shipping on all orders above $100. The MK-677 for sale comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration. Our great customer service and fast shipping help us stand out from the competition.

Can the effects of Ibutamoren be observed immediately?

The observable effects of Ibutamoren in research settings may vary depending on the experimental conditions. Researchers should monitor and record observations at regular intervals as part of their study.

Can Ibutamoren be used in combination with other research compounds?

Yes, Ibutamoren is often studied in combination with other research compounds. Researchers may choose to explore potential synergistic effects or interactions by combining it with other agents in controlled experiments.

Summary

MK677 or Ibutamoren is a growth hormone secretagogue. Multiple clinical studies have shown that it may have the potential to increase levels of GH and IGF-1.

Aside from that, some studies suggest a potential safety profile, but Ibutamoren is not approved for human use, and its safety is not fully established and MK-677 remains an experimental compound. . However, it is yet to be approved for human consumption and can only be acquired for laboratory research use.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).

Our content is intended to be used and must be used for informational purposes only. It is very important to do your own analysis and research from Trusted Sources before making any purchase based on your own personal circumstances. You should independently research and verify any information that you find on our Website and wish to rely upon.

By completing and paying for your order, you agree to our Terms and Conditions. Customer satisfaction is our number one priority, if you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY not for veterinary or human usage.

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103 reviews for Ibutamoren (MK-677)

  1. User Avatar: Robert Minarik

    Robert Minarik –

    The product arrived safely. Thanks

  2. Olly Mitchels –

    Outstanding quality.

  3. Bret S. –

    Works very quickly. Great stuff. A little nausea at first. Does cause a rise in blood sugar level.

  4. Jackson Lenas –

    Super quality!

  5. Jake Hill –

    Amazing product with speedy results.

  6. Lyle Turner –

    Fantastic product, fast shipping and very helpful customer service.

  7. James Brown –

    Really helps to assist lean muscle gains.

  8. Donald Hagan –

    Definite strength improvement. Will recommend your product.

  9. Robin Adair –

    Been lifting heavier than ever.

  10. Julie M –

    Fast shipping.
    Seeing results even in skin, nail, hair health

  11. Steven Brewer –

    Can highly recommend this MK!

  12. Daniel Ulster –

    The gains are so worth it!

  13. Tommy Vargas –

    Great quality. Slept way better and gains came fast. Definitely recommending this to my friends

  14. Arthur Rendell –

    Muscle gains fantastic.

  15. bigcajun-2784 –

    This is my go to to add to any stack. Just adding with regular trt is a guaranteed 15 to 20 pound increase in a few week while keeping roughly half of it after its finished. Increased appetite, better sleep and quicker recovery

  16. Dave –

    Worth the buy! This is a must have product!

  17. Nick Kling (verified owner) –

    A little pip for a few days with the injectable. Besides that it works well and you feel it instantly. Shipping as with all products us quick and secure .

  18. vasquezjacob203 –

    This product helped me gain several kilos of lean muscle in just 1 cycle. Amazing!

  19. Mohammed S –

    Great product for fast gains and overall health ,excellent customer service

  20. Anan Izar –

    Customer service was amazing and very friendly. And about the product, I’m Still using it and it’s working great on me.

  21. Anonymous –

    Hey PureRawz! Thank you, I just want to notify you guys that I received my order today. You guys really have an amazing customer service. Good job.

  22. Cody Corbett –

    Had good results gained weight but be prepared for being super hungry

  23. Brian Picariello –

    Great recovery and joints felt way better plus increased appetite

  24. Neil Shipton –

    Fast shipping. Good packaging. Great recovery after training hard.

  25. Ralph Wood –

    This stuff works, simply said. I feel fully recovered after crucial workouts. If you are looking to feel better and more energized , then this is what you need!

  26. Noel Zimmerman –

    Real results!

  27. Dough Sterling –

    Never had anything like this, to be honest. Minimal after effects. Just perfect!

  28. Anonymous –

    Strength gains for me.

  29. Vaughan D. –

    Very happy with what I received. One of the best Mk’s on the market.

  30. William Jenkins –

    I am impressed – older bodies take longer to react and this has given me the needed boost.

  31. rubenb –

    Best product on the market, my lab rats love it

  32. D. Bechtelar –

    Took me a few weeks but now I’m starting to really see a difference in my lifts. I feel more ‘alert’ while lifting if that makes sense. I feel more focus and my lifts feel solid and tight.

  33. nickm989 (verified owner) –

    Best Sarms available 💯

  34. Christopher (verified owner) –

    The injectable MK is unique and amazing, just be patient they are slow in shipping.

  35. Christopher (verified owner) –

    Injectable MK is unique and amazing !

  36. Clayton K –

    Arrived in a timely manner and works great.

  37. Grant Mansill –

    Great quality, saw strength gains within the first two weeks.

  38. Ryan –

    Customer service is great. Product is high quality and works very well.

  39. Frank Bent –

    Very good product! My first time and will come back again

  40. Endri Dedja –

    It helps me gain muscle. I bought here and New Sarms they are the best

  41. Mohan Ali (verified owner) –

    Let’s start by shipping….. these guys ON POINT! You’ll receive your shipment within 12 days as expected. The packaging is above and beyond any product I’ve purchased from any other supplier. Now the main reason of this review, the MK677!!! This is by far the best product I’ve ever purchased. If you know how to use it and when to use it, I can’t tell you enough about the results. I use MK677 with RAD 140 which’s another phenomenal product from PureRawZ and the gain I receive is what I expect.

    This is not a magical product y’all, however, the results is magical if you follow the proper process and let the muscles gain through hard work and determination. Eat healthy, work hard and enjoy the gain!

  42. LaQuintice (verified owner) –

  43. Ron Snitkovsky (verified owner) –

  44. Michael (verified owner) –

    Has helped me stay low in body fat but I see that I look bigger and feel stronger

  45. Carlos Gabriel Carranza R. (verified owner) –

    Carlos

  46. Verified Buyer (verified owner) –

  47. joshua (verified owner) –

    Glad to say this is the real stuff.

  48. Verified Buyer (verified owner) –

  49. James (verified owner) –

    Everything was good with this order.

  50. Matthew (verified owner) –

  51. Andrew (verified owner) –

    Great product. The health benefits were noticeable on day 2. I’ve ordered another 2 month supply. Delivery was 5 days and discrete.

  52. Verified Buyer (verified owner) –

  53. Verified Buyer (verified owner) –

    works. not super strong but will definitely notice it.

  54. James Brock (verified owner) –

    Everything was good, alittle late on delivery, USPS I assume, thank you

  55. Verified Buyer (verified owner) –

    Good product

  56. Michael G. (verified owner) –

    Used to take this few years ago back on it the hunger is like next day kicks in sleep is harder and growth kicks in about 3 months for me love it

  57. Jeremy (verified owner) –

    Subject saw improvements in strength and recovery

  58. sergio (verified owner) –

  59. Andrew (verified owner) –

  60. Anonymous (verified owner) –

  61. brent o. (verified owner) –

  62. deniyel v. (verified owner) –

    effects noticeable

  63. Anonymous (verified owner) –

  64. Joseph (verified owner) –

  65. Frank D. (verified owner) –

  66. Devin Cullum (verified owner) –

  67. Richard (verified owner) –

    Helps me put on weight.

  68. Nicole B. (verified owner) –

  69. chad lucas (verified owner) –

  70. Greg Moore (verified owner) –

    Good stuff

  71. Ron Snitkovsky (verified owner) –

  72. Tanner (verified owner) –

  73. Jim Ryan (verified owner) –

    This product is outstanding and delivers as advertised.

  74. Branden B. (verified owner) –

  75. Peter (verified owner) –

  76. Anonymous (verified owner) –

  77. lucas l. (verified owner) –

  78. David –

    Got it for my dad he loved it

  79. admin (store manager) –

    Perfect Product

  80. Peter (verified owner) –

    Product works as described. Very impressive.

  81. Diego Majano (verified owner) –

  82. Josh Powell (verified owner) –

    It’s important to note glycogen uptake with this product is high.

  83. Branden Barnhart (verified owner) –

  84. Glenn M. (verified owner) –

    Raw amazing products

  85. Devin G. (verified owner) –

  86. Kevin S. (verified owner) –

  87. Will (verified owner) –

    Has performed extremely well in research.

  88. Thomas (verified owner) –

  89. Zachary Barajas (verified owner) –

  90. Drew (verified owner) –

  91. chad (verified owner) –

    Great priduct

  92. Robert alexander (verified owner) –

  93. Floyd (verified owner) –

    Excellent

  94. Kelly (verified owner) –

    Good product great price

  95. Shaun Weber (verified owner) –

    First time experimenting with sarms…after 4 weeks a low dose around 8mg a day for the first 4w I definitely noticed increased muscle

  96. liyivix666 –

    It really works great for muscle growth

  97. yicej77021 –

    Helps with muscle growth and sleep. Feeling more energized too.

  98. Dean Hadley (verified owner) –

    Incredible shipping less than 3 days 1 of which was a holiday.
    Ordered the liquid 17 mg per ml what’s the recommended dosage for a 33 year old 160 lb lab rat stacking ostarine?
    All questions are for research purposes or hypothetical.

  99. Felipe Toscano (verified owner) –

    Amazing products great results worth every penny

  100. masonlaird555 (verified owner) –

    I got mine in less than a week and has helped me put on 15 pounds in 2 months.

  101. lightninglloyd2003 (verified owner) –

    Works well

  102. b_ristow –

    I have reviewed MK677 over a few different online stores and purerawz seems to be the one that my body either reacts to better…. or it’s a better product. Those other places I would have to take 25-30 mg to have similar effects to the 17-20 mg from purerawz. I also noticed better size throughout the time. Thank you.

  103. Paul M. (verified owner) –

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